Roger Stimson is an emergency-room nurse in New Orleans, trying to forget his past as an intelligence and bio-chemical officer who almost single-handedly stopped an alien invasion of Earth by the Enochians. Now, eight years later, the Enochians are back, and one alien named Dingo claims that a faction of his people wants to restart the war by assassinating the U.S. President. Dingo drags Stimson into intrigue, conspiracy, and interstellar gamesmanship. Soon the two find themselves on the run, accused of murder and dodging professional killers who want them silenced. For Stimson his only way out is to follow Dingo's lead and stop an assassination that would lead to a restart of a war that Earth would not survive this time.