Three victims disappear off the streets of New York, never to be seen again: a high school janitor, a top New York model, and a barkeep. Three people who have seemingly no connection to each other. Yet all three are connected to Louise, a teenage runaway who has recently gone missing.
Louise came to the big city to create a new life for herself. That life ended when a cruel sadist abducted her, mutilated her body and face, and dumped her remains in the East River. Not quite dead, she floated ashore to the ruins of an abandoned church. There she was found and saved — but what saved her wasn’t human. He hasn’t been human in well over one hundred years.
The underground calls him the Doctor, a shadow-figure who wields the powers of life and death in equal measure, and for his own dubious purposes. A Victorian-era, genius surgeon who has discovered the secret to not only defeating tissue rejection, but immortality itself, he rebuilds Louise, giving her a new face, a new identity, and a taste for revenge.
Now Louise is back, remade and redesigned into a perfect murder machine by the Doctor’s talented hands. She is cutting a path of vengeance through the echelons of the city, from its lowest bowels to its loftiest towers, and nothing in heaven — or hell — can stop her.